Top ▲

Interleukin-15 receptor subunit α

Click here for help

Immunopharmacology Ligand target has curated data in GtoImmuPdb

Target id: 1702

Nomenclature: Interleukin-15 receptor subunit α

Family: IL-2 receptor family

Quaternary Structure: Complexes
Interleukin-15 receptor
Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 267 10p15.1 IL15RA interleukin 15 receptor subunit alpha
Mouse 1 263 2 8.97 cM Il15ra interleukin 15 receptor, alpha chain
Rat - - Il15ra interleukin 15 receptor subunit alpha
Previous and Unofficial Names Click here for help
CD215 | interleukin 15 receptor, alpha | interleukin 15 receptor
Database Links Click here for help
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas

Download all structure-activity data for this target as a CSV file go icon to follow link

Key to terms and symbols Click column headers to sort
Ligand Sp. Action Value Parameter Reference
IL-15 {Sp: Human} Peptide Click here for species-specific activity table Immunopharmacology Ligand Hs Agonist 11.4 pKd 1
pKd 11.4 (Kd 3.8x10-12 M) [1]
Description: Binding of recombinant hIL-15 to IL-15Rα subunit using Surface Plasmon Resonance (SPR)
Immunopharmacology Comments
This is the ligand binding subunit of the functional IL-15 receptor complex.
Immuno Process Associations
Immuno Process:  Cytokine production & signalling
Immuno Process:  Inflammation
Immuno Process:  Cellular signalling
Immuno Process:  Immune regulation
Immuno Process:  Immune system development


Show »

1. Liu X, Kirk PB, Chang T, Charych DH. (2017) Conjugates of an il-15 moiety and a polymer. Patent number: US20170035898. Assignee: Nektar Therapeutics. Priority date: 03/04/2014. Publication date: 09/02/2017.

How to cite this page

IL-2 receptor family: Interleukin-15 receptor subunit α. Last modified on 31/07/2017. Accessed on 20/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY,