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Quaternary Structure: Complexes |
Interleukin-31 receptor |
Gene and Protein Information | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | 1 | 732 | 5q11.2 | IL31RA | interleukin 31 receptor A | |
Mouse | 1 | 716 | 13 D2.2 | Il31ra | interleukin 31 receptor A | |
Rat | - | 718 | 2q14 | Il31ra | interleukin 31 receptor A |
Previous and Unofficial Names | |
CRL | CRL3 | interleukin-31 receptor subunit alpha | GPL | Glmr | NR10 [1] |
Database Links | |
Alphafold | Q8NI17 (Hs), Q8K5B1 (Mm) |
CATH/Gene3D | 2.60.40.10 |
ChEMBL Target | CHEMBL4630894 (Hs) |
Ensembl Gene | ENSG00000164509 (Hs), ENSMUSG00000050377 (Mm), ENSRNOG00000042080 (Rn) |
Entrez Gene | 133396 (Hs), 218624 (Mm), 688622 (Rn) |
Human Protein Atlas | ENSG00000164509 (Hs) |
KEGG Gene | hsa:133396 (Hs), mmu:218624 (Mm), rno:688622 (Rn) |
OMIM | 609510 (Hs) |
Pharos | Q8NI17 (Hs) |
RefSeq Nucleotide | NM_001242636 (Hs), NM_139299 (Mm), NM_001257278 (Rn) |
RefSeq Protein | NP_001229565 (Hs), NP_647460 (Mm), NP_001244207 (Rn) |
UniProtKB | Q8NI17 (Hs), Q8K5B1 (Mm) |
Wikipedia | IL31RA (Hs) |
Download all structure-activity data for this target as a CSV file
Antibodies | |||||||||||||||||||||||||||||||||||||||||||||||||||
Key to terms and symbols | Click column headers to sort | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Immuno Process Associations | ||
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General Comments |
The IL-31 receptor subunit α functions a monomer and as part of a receptor complex with the oncostatin M receptor (OSMR). It is a type I cytokine receptor that is involved in IL-31 signalling which is mediated via activation of STAT3 and STAT5. |
1. Kuramochi T, Kasutani K, Ohyama S, Tsunoda H, Igawa T, Tachibana T, Shiraiwa H, Esaki K. (2013) Anti-NR10 antibody and use thereof. Patent number: US8575317 B2. Assignee: Chugai Seiyaku Kabushiki Kaisha. Priority date: 05/12/2007. Publication date: 05/11/2013.
IL-6 receptor family: Interleukin-31 receptor, α subunit. Last modified on 17/10/2018. Accessed on 11/11/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1710.