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Interleukin-12 receptor, β1 subunit

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Immunopharmacology Ligand target has curated data in GtoImmuPdb

Target id: 1715

Nomenclature: Interleukin-12 receptor, β1 subunit

Family: IL-12 receptor family

Quaternary Structure: Complexes
Interleukin-12 receptor
Interleukin-23 receptor
Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 662 19p13.11 IL12RB1 interleukin 12 receptor subunit beta 1
Mouse 1 738 8 34.21 cM Il12rb1 interleukin 12 receptor, beta 1
Rat - - Il12rb1 interleukin 12 receptor subunit beta 1
Previous and Unofficial Names Click here for help
CD212 | interleukin 12 receptor, beta 1 | interleukin 12 receptor
Database Links Click here for help
Alphafold
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Pharos
UniProtKB
Wikipedia
Immunopharmacology Comments
This protein is a subunit of both the IL-12 and IL-23 cytokine receptors.
Immuno Process Associations
Immuno Process:  Inflammation
Immuno Process:  T cell (activation)
Immuno Process:  B cell (activation)
Immuno Process:  Immune regulation
Immuno Process:  Immune system development
Immuno Process:  Cytokine production & signalling
Immuno Process:  Chemotaxis & migration
Immuno Process:  Cellular signalling

How to cite this page

IL-12 receptor family: Interleukin-12 receptor, β1 subunit. Last modified on 22/03/2017. Accessed on 16/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1715.