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Interleukin-12 receptor, β2 subunit

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Immunopharmacology Ligand target has curated data in GtoImmuPdb

Target id: 1716

Nomenclature: Interleukin-12 receptor, β2 subunit

Family: IL-12 receptor family

Quaternary Structure: Complexes
Interleukin-12 receptor
Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 862 1p31.3 IL12RB2 interleukin 12 receptor subunit beta 2
Mouse 1 874 6 30.81 cM Il12rb2 interleukin 12 receptor, beta 2
Rat - - Il12rb2 interleukin 12 receptor subunit beta 2
Previous and Unofficial Names Click here for help
interleukin 12 receptor, beta 2 | Ifnm | interleukin 12 receptor
Database Links Click here for help
Alphafold
CATH/Gene3D
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Pharos
UniProtKB
Wikipedia
Immunopharmacology Comments
This protein is a subunit of the functional receptor heterodimer for the IL-12 cytokine.
Immuno Process Associations
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 7 GO processes
GO:0004896 cytokine receptor activity IBA
GO:0019221 cytokine-mediated signaling pathway IBA
GO:0032729 positive regulation of interferon-gamma production IDA
GO:0034097 response to cytokine IMP
GO:0035722 interleukin-12-mediated signaling pathway TAS
GO:0070757 interleukin-35-mediated signaling pathway TAS
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GO:0032609 interferon-gamma production IEA

How to cite this page

IL-12 receptor family: Interleukin-12 receptor, β2 subunit. Last modified on 07/04/2017. Accessed on 21/09/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1716.