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Interferon α/β receptor 2

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Immunopharmacology Ligand target has curated data in GtoImmuPdb

Target id: 1724

Nomenclature: Interferon α/β receptor 2

Family: Interferon receptor family

Quaternary Structure: Complexes
Interferon-α/β receptor
Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 515 21q22.11 IFNAR2 interferon alpha and beta receptor subunit 2
Mouse 1 513 16 52.82 cM Ifnar2 interferon (alpha and beta) receptor 2
Previous and Unofficial Names Click here for help
IFNABR | interferon (alpha, beta and omega) receptor 2
Database Links Click here for help
Alphafold
CATH/Gene3D
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Pharos
UniProtKB
Wikipedia
Immunopharmacology Comments
A subunit of the functional receptor for various interferons (NOT interferon γ).
Immuno Process Associations
Immuno Process:  Inflammation
GO Annotations:  Associated to 2 GO processes
GO:0004905 type I interferon receptor activity IDA
GO:0060337 type I interferon-mediated signaling pathway IDA
Immuno Process:  Immune regulation
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 6 GO processes
GO:0004896 cytokine receptor activity IBA
GO:0004905 type I interferon receptor activity IDA
GO:0019221 cytokine-mediated signaling pathway IBA
GO:0035455 response to interferon-alpha IDA
GO:0035456 response to interferon-beta IMP
GO:0060337 type I interferon-mediated signaling pathway IDA

How to cite this page

Interferon receptor family: Interferon α/β receptor 2. Last modified on 10/04/2017. Accessed on 08/12/2022. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1724.