Quaternary Structure: Complexes

Interleukin-1 receptor, type I

Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	569	2q11.2-q12.1	IL1R1	interleukin 1 receptor type 1
Mouse	1	576	1 18.81 cM	Il1r1	interleukin 1 receptor, type I
Rat	1	576	9q22	Il1r1	interleukin 1 receptor type 1

Previous and Unofficial Names

CD121A | IL1RA | CD121 antigen-like family member A | IL-1R-alpha | interleukin 1 beta receptor type 1 short transmembrane form | interleukin 1 beta receptor type 1 soluble form | interleukin 1 bete receptor type 1 long transmembrane form | interleukin-1 receptor alpha | interleukin 1 receptor

Database Links
Alphafold	P14778 (Hs), P13504 (Mm), Q02955 (Rn)
CATH/Gene3D	3.40.50.10140, 2.60.40.10
ChEMBL Target	CHEMBL1959 (Hs), CHEMBL2189148 (Mm)
DrugBank Target	P14778 (Hs)
Ensembl Gene	ENSG00000115594 (Hs), ENSMUSG00000026072 (Mm), ENSRNOG00000014504 (Rn)
Entrez Gene	3554 (Hs), 16177 (Mm), 25663 (Rn)
Human Protein Atlas	ENSG00000115594 (Hs)
KEGG Gene	hsa:3554 (Hs), mmu:16177 (Mm), rno:25663 (Rn)
OMIM	147810 (Hs)
Pharos	P14778 (Hs)
UniProtKB	P14778 (Hs), P13504 (Mm), Q02955 (Rn)
Wikipedia	IL1R1 (Hs)

Immunopharmacology Comments

This is one of the subunits of the functional IL-1 receptor type I heterodimer.

Immuno Process Associations

Immuno Process:  T cell (activation)

Immuno Process:  B cell (activation)

Immuno Process:  Cytokine production & signalling

Immuno Process:  Inflammation

Immuno Process:  Immune regulation

Immuno Process:  Chemotaxis & migration