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Interleukin 1 receptor, type I

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Immunopharmacology Ligand target has curated data in GtoImmuPdb

Target id: 1734

Nomenclature: Interleukin 1 receptor, type I

Family: Immunoglobulin-like family of IL-1 receptors

Quaternary Structure: Complexes
Interleukin-1 receptor, type I
Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 569 2q11.2-q12.1 IL1R1 interleukin 1 receptor type 1
Mouse 1 576 1 18.81 cM Il1r1 interleukin 1 receptor, type I
Rat 1 576 9q22 Il1r1 interleukin 1 receptor type 1
Previous and Unofficial Names Click here for help
CD121A | IL1RA | CD121 antigen-like family member A | IL-1R-alpha | interleukin 1 beta receptor type 1 short transmembrane form | interleukin 1 beta receptor type 1 soluble form | interleukin 1 bete receptor type 1 long transmembrane form | interleukin-1 receptor alpha | interleukin 1 receptor
Database Links Click here for help
Alphafold
CATH/Gene3D
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Pharos
UniProtKB
Wikipedia
Immunopharmacology Comments
This is one of the subunits of the functional IL-1 receptor type I heterodimer.
Immuno Process Associations
Immuno Process:  T cell (activation)
Immuno Process:  B cell (activation)
Immuno Process:  Cytokine production & signalling
Immuno Process:  Inflammation
Immuno Process:  Immune regulation
Immuno Process:  Chemotaxis & migration

How to cite this page

Immunoglobulin-like family of IL-1 receptors: Interleukin 1 receptor, type I. Last modified on 22/03/2017. Accessed on 21/07/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1734.