Quaternary Structure: Complexes

Interleukin-17 receptor

Interleukin-25 receptor

Interleukin-17C receptor

Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	866	22q11.1	IL17RA	interleukin 17 receptor A
Mouse	1	864	6 56.95 cM	Il17ra	interleukin 17 receptor A
Rat	-	-		Il17ra	interleukin 17 receptor A

Previous and Unofficial Names

CD217 | VDw217 | Interleukin-17 α receptor

Database Links
Alphafold	Q96F46 (Hs), Q60943 (Mm)
ChEMBL Target	CHEMBL3580485 (Hs)
Ensembl Gene	ENSG00000177663 (Hs), ENSMUSG00000002897 (Mm), ENSRNOG00000011153 (Rn)
Entrez Gene	23765 (Hs), 16172 (Mm), 312679 (Rn)
Human Protein Atlas	ENSG00000177663 (Hs)
KEGG Gene	hsa:23765 (Hs), mmu:16172 (Mm), rno:312679 (Rn)
OMIM	605461 (Hs)
Pharos	Q96F46 (Hs)
UniProtKB	Q96F46 (Hs), Q60943 (Mm)
Wikipedia	IL17RA (Hs)

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Antibodies
Key to terms and symbols		Click column headers to sort
Antibody Sp. Action Value Parameter Reference brodalumab Hs Binding 9.2 pKd 1 ⤷ pKd 9.2 (Kd 6.9x10-10 M) [1]

Immunopharmacology Comments

This protein is a common subunit shared by the heterodimeric receptors for interleukins 17 (A, B , C and F) and 25.

Immuno Process Associations

Immuno Process:  Cytokine production & signalling

Immuno Process:  Inflammation

Immuno Process:  Immune regulation

Immuno Process:  Chemotaxis & migration