Quaternary Structure: Subunits

Interleukin 5 receptor, α subunit (Ligand-binding subunit)

Cytokine receptor common β subunit (Other subunit)

Natural/Endogenous Ligands
IL-5 {Sp: Human}

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Agonists
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Ligand Sp. Action Value Parameter Reference IL-5 {Sp: Human} Hs Agonist - - ⤷

Antagonists
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference YM90709 Hs Antagonist - - 1 ⤷ [1]

Immunopharmacology Comments

The functional IL-5 receptor is a heterodimer consisting of the ligand binding interleukin-5 receptor subunit α (IL5RA) and CSF2RB (cytokine receptor common β subunit). CSF2RB is required for the formation of the functional receptors for IL-3, IL-5 and GM-CSF.