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Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).
CYP1, 2 and 3 family enzymes are involved in the biotransformation of xenobiotics, including clinically used drugs. Polymorphisms, particularly in the CYP2 family, impact upon an individual's response to drugs [31], including the risk of adverse drug reactions, drug efficacy and dose requirement.
CYP2A6 C Show summary » More detailed page |
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CYP2A7 C Show summary » |
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CYP2A13 C Show summary » |
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CYP2B6 C Show summary » More detailed page |
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CYP2C8 C Show summary » More detailed page |
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CYP2C9 C Show summary » More detailed page |
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CYP2C18 Show summary » |
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CYP2C19 C Show summary » |
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CYP2D6 C Show summary » More detailed page |
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CYP2E1 C Show summary » More detailed page |
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CYP2F1 C Show summary » |
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CYP2J2 C Show summary »
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Database page citation (select format):
Concise Guide to PHARMACOLOGY citation:
Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.