From August 18th 2026, GtoPdb will require users to register to use the website. Please see our blog post for more information.

mutant ANP   Click here for help

GtoPdb Ligand ID: 10211

Synonyms: mANP | mutant atrial natriuretic peptide
Comment: This is a naturally occurring variant of human atrial natriuretic peptide A (ANP; NPPA) [2]. It is a fusion that contains the full 28 amino acids of ANP plus a 12 amino acid C-terminal extension. In comparison to normal ANP this longer peptide exhibits enhanced blood pressure-lowering, renal-enhancing, and aldosterone-suppressing actions in vivo.
Species: Human