DO264

Ligand id: 10250

Name: DO264

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 103.63
Molecular weight 557.07
XLogP 6.49
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Selectivity at enzymes
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
αβ-Hydrolase 12 Hs Inhibitor Inhibition 8.0 pIC50 - 2
pIC50 8.0 (IC50 1.1x10-8 M) [2]