vilobelimab   Click here for help

GtoPdb Ligand ID: 11346

Synonyms: CaCP-29 | IFX-1
Compound class: Antibody
Comment: Vilobelimab (IFX-1) is a chimeric IgG4 monoclonal antibody against the terminal complement component, anaphylatoxin C5a. It was developed for potential to treat complement mediated inflammatory diseases. Vilobelimab blocks C5a/C5aR1 signalling in subsets of myeloid-derived suppressor cells (MDSCs) and neutrophils.
Targets where the ligand is described in the comment field
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