RLF-(A11-B10)-isopeptide amideA26 (xA11-B10)   Click here for help

GtoPdb Ligand ID: 11922

Comment: RLF-(A11-B10)-isopeptide amideA26 (xA11-B10) is a derivative of relaxin-like factor (RLF/INSL3) in which the interchain disulphide bond is replaced with an isopeptide bond. This derivative behaves as a RXFP2 antagonist (Kd ~2 nM) [1].
Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
RXFP2 Hs Antagonist Antagonist - - - 1
[1]