Ligand id: 1241

Name: N-[3H]methylhistamine    

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 43.84
Molecular weight 125.1
XLogP -0.13
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
H3 receptor Hs Agonist Full agonist 9.1 pKd - 1
pKd 9.1 [1]
H3 receptor Rn Agonist Full agonist 9.1 pKd - 2
pKd 9.1 [2]
H4 receptor Hs Agonist Full agonist 7.8 pKd - 1
pKd 7.8 [1]