Synonyms: MK-191 | Pondocillin®
Compound class:
Synthetic organic
Comment: Pivampicillin is a pivaloyloxymethyl ester and prodrug of the β-lactam antibacterial compound ampicillin [1]. It has improved oral bioavailability compared to ampicillin and is rapidly hydrolysed to the active form following absorption from the gastrointestinal tract [3].
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Bioactivity Comments |
We have been unable to identify quantitative data for the antibacterial activity of pivampicillin. As a prodrug it is likely that antibacterial activity will be associated with the active form, ampicillin. |