Synonyms: MTK-458
Compound class:
Synthetic organic
Comment: MTK458 is an oral brain penetrant PTEN induced kinase 1 (PINK1) activator [1]. In vivo MTK458 drives clearance of α-synuclein pathology in Parkinson's models.
|
|
Selectivity at enzymes | ||||||||||||||||||||||||||||||||||
Key to terms and symbols | Click column headers to sort | |||||||||||||||||||||||||||||||||
|