muscarinic toxin β   Click here for help

GtoPdb Ligand ID: 13152

Synonyms: Adrenergic toxin rho-elapitoxin-Dp1a | MTβ | rho-EPTX-Dp1a
Comment: Muscarinic toxin β is a snake venom component produced by the black mamba (Dendroaspis polylepis polylepis). It antagonises human adrenoceptors [1], but despite its name has only weak affinity for mammalian muscarinic receptors.
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
α1B-adrenoceptor Hs Antagonist Antagonist 8.0 pKi - 1
pKi 8.0 [1]