agouti   

GtoPdb Ligand ID: 1329

Synonyms: ASIP
Species: Mouse
Natural/Endogenous Targets
Target
MC1 receptor
MC3 receptor
MC4 receptor
MC5 receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
MC1 receptor Mm Antagonist Inverse agonist 8.6 pKd - 1-2
pKd 8.6 [1-2]
MC4 receptor Mm Antagonist Inverse agonist 7.3 pKd - 1
pKd 7.3 [1]
MC5 receptor Mm Antagonist Inverse agonist 4.9 pKd - 1
pKd 4.9 [1]
MC3 receptor Mm Antagonist Inverse agonist 6.7 pIC50 - 1
pIC50 6.7 [1]