PYY-(13-36) (mouse, rat, pig)   

GtoPdb Ligand ID: 1516

Synonyms: porcine peptide tyrosine tyrosine (13-36) | porcine peptide YY (13-36) | rat peptide tyrosine tyrosine (13-36) | rat peptide YY (13-36)
Comment: Synthetic fragment of rodent/porcine PYY. PYY shares the same amino acid sequence across the three species
Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Y2 receptor Hs Agonist Full agonist 8.8 – 9.4 pKi - 1,3
pKi 8.8 – 9.4 [1,3]
Y1 receptor Rn Agonist Full agonist 7.5 pKi - 2
pKi 7.5 [2]
Y5 receptor Hs Agonist Full agonist 7.1 pKi - 4
pKi 7.1 [4]
Y5 receptor Rn Agonist Full agonist 7.1 pKi - 4
pKi 7.1 [4]
Y4 receptor Rn Agonist Full agonist 6.2 – 7.5 pKi - 2,5
pKi 7.5 [2]
pKi 6.2 [5]