dynorphin A-(1-8)   Click here for help

GtoPdb Ligand ID: 1621

Synonyms: dynorphin A (1-8)
Species: Human, Mouse, Rat
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Natural/Endogenous Targets
Target
δ receptor
κ receptor
μ receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
κ receptor Ligand is endogenous in the given species Hs Agonist Full agonist 8.0 – 9.9 pKi - 1-3,5
pKi 8.0 – 9.9 [1-3,5]
δ receptor Ligand is endogenous in the given species Hs Agonist Partial agonist 8.4 pKi - 3
pKi 8.4 [3]
μ receptor Ligand is endogenous in the given species Hs Agonist Full agonist 8.4 pKi - 3
pKi 8.4 [3]
κ receptor Ligand is endogenous in the given species Mm Agonist Full agonist 9.7 pIC50 - 4
pIC50 9.7 [4]