uridine triphosphate

Ligand id: 1734

Name: uridine triphosphate

Abbreviated name: UTP

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 15
Hydrogen bond donors 7
Rotatable bonds 8
Topological polar surface area 293.8
Molecular weight 483.97
XLogP -5.54
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Natural/Endogenous Targets
Target
P2Y11 receptor
P2Y2 receptor
P2Y4 receptor
P2Y6 receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
P2Y2 receptor Hs Agonist Full agonist 8.1 pEC50 - 4-5
pEC50 8.1 [4-5]
P2Y4 receptor Hs Agonist Full agonist 6.3 pEC50 - 3
pEC50 6.3 [3]
P2Y4 receptor Rn Agonist Partial agonist 5.6 pEC50 - 1
pEC50 5.6 [1]
P2Y6 receptor Hs Agonist Partial agonist 5.2 pEC50 - 2
pEC50 5.2 [2]
P2Y11 receptor Hs Agonist Full agonist 5.2 pEC50 - 6
pEC50 5.2 [6]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields