PTHrP-(1-21)/PTH-(22-34) (human)   

GtoPdb Ligand ID: 1788

Synonyms: hybrid of human PTHrP and human PTH
Comment: Synthetic hybrid of human PTHrP and PTH 22-34
Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
PTH1 receptor Hs Agonist Full agonist 7.7 pIC50 - 1
pIC50 7.7 [1]
PTH2 receptor Hs Antagonist Antagonist 7.0 – 8.0 pIC50 - 1-2
pIC50 7.0 – 8.0 [1-2]
PTH2 receptor Rn Antagonist Antagonist 5.5 pIC50 - 2
pIC50 5.5 [2]