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Synonyms: hybrid of human PTHrP and human PTH
Compound class: Peptide or derivative
Comment: Synthetic hybrid of human PTHrP and PTH 22-34
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Gardella TJ, Luck MD, Jensen GS, Usdin TB, Jüppner H. (1996)
Converting parathyroid hormone-related peptide (PTHrP) into a potent PTH-2 receptor agonist.
J. Biol. Chem., 271 (33): 19888-93. [PMID:8702701]
2. Goold CP, Usdin TB, Hoare SR. (2001)
Regions in rat and human parathyroid hormone (PTH) 2 receptors controlling receptor interaction with PTH and with antagonist ligands.
J. Pharmacol. Exp. Ther., 299 (2): 678-90. [PMID:11602681]