Ligand id: 2046

Name: L-054,522

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 5
Rotatable bonds 16
Topological polar surface area 167.34
Molecular weight 645.36
XLogP 3.38
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
SST2 receptor Hs Agonist Full agonist 11.0 pKi - 1
pKi 11.0 [1]