[111In,90Y]DOTA-LAN   Click here for help

GtoPdb Ligand ID: 2056

Synonyms: DOTA-conjugated peptide | YIII-DOTA-LAN [1]
 Ligand is labelled  Ligand is radioactive
Comment: Synthetic peptide lanreotide (BIM 23014) conjugated with DOTA and labelled with yttrium (90Y) on tyrosine residue 3 and indium (111In). The exact structure of this ligand is not specified in the reference. For the structures of DOTA and lanreotide see the individual ligand pages.
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
SST5 receptor Hs Agonist Full agonist 7.8 pIC50 - 1
pIC50 7.8 [1]
SST2 receptor Hs Agonist Full agonist 7.6 pIC50 - 1
pIC50 7.6 [1]
SST3 receptor Hs Agonist Full agonist 6.5 pIC50 - 1
pIC50 6.5 [1]