[Ac-His1]PACAP-27

Ligand id: 2263

Name: [Ac-His1]PACAP-27

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
PAC1 receptor Rn Agonist Agonist 8.0 – 8.3 pKi - 1
pKi 8.3 (Ki 5x10-9 M) [1]
Description: inhibition of [125I]-[Ac-His1]PACAP-27 binding to membranes from CHO cells stably expressing the rat PAC1 receptor isoform including the hop1 exon
pKi 8.0 (Ki 1x10-8 M) [1]
Description: inhibition of [125I]-[Ac-His1]PACAP-27 binding to membranes from CHO cells stably expressing the rat PAC1 receptor isoform lacking the hip and hop exons