coenzyme A

Ligand id: 3044

Name: coenzyme A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 22
Hydrogen bond donors 9
Rotatable bonds 20
Topological polar surface area 414.79
Molecular weight 767.12
XLogP -5.83
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Enzymes Catalysing Reactions with this Compound as a Substrate or Product
Enzyme EC number Reaction Reference
acetyl-CoA acetyltransferase 1 1
hydroxymethylglutaryl-CoA synthase 2
ceramide synthase 1
acetyl-CoA acetyltransferase 2
ceramide synthase 4
serine palmitoyltransferase long chain base subunit 1
hydroxymethylglutaryl-CoA synthase 1
ceramide synthase 5
choline O-acetyltransferase
ceramide synthase 2
ceramide synthase 6
serine palmitoyltransferase long chain base subunit 2
serine palmitoyltransferase long chain base subunit 3
ceramide synthase 3
hydroxymethylglutaryl-CoA reductase
Ligand mentioned in the following text fields