M65   Click here for help

GtoPdb Ligand ID: 3305

Synonyms: des-(Gln25-Gln41)-maxadilan | maxadilan Δ25-41
Compound class: Peptide
Comment: The properties of this maxadilan analogue were first described in [2].
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
PAC1 receptor Hs Antagonist Antagonist 6.6 – 6.8 pIC50 - 1
pIC50 6.8 (IC50 1.496x10-7 M) [1]
Description: inhibition of cyclic AMP formation stimulated by 0.1nM PACAP-27 in CHO cells stably expressing recombinant receptor
pIC50 6.6 (IC50 2.774x10-7 M) [1]
Description: inhibition of calcium influx stimulated by 30nM PACAP-27 in CHO cells stably expressing recombinant receptor
Ligand mentioned in the following text fields