[3H]LXA4

Ligand id: 3411

Name: [3H]LXA4    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 14
Topological polar surface area 97.99
Molecular weight 354.24
XLogP 3.04
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
FPR2/ALX Hs Agonist Full agonist 9.1 – 9.3 pKd - 2-3
pKd 9.1 – 9.3 (Kd 7x10-10 – 5x10-10 M) [2-3]
FPR2/ALX Mm Agonist Full agonist 8.8 pKd - 4
pKd 8.8 (Kd 1.5x10-9 M) [4]
FPR2/ALX Rn Agonist Full agonist 8.3 pKd - 1
pKd 8.3 (Kd 5x10-9 M) [1]