[3H]LTB4

Ligand id: 3413

Name: [3H]LTB4    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 14
Topological polar surface area 77.76
Molecular weight 336.23
XLogP 4.5
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
BLT1 receptor Hs Agonist Full agonist 9.8 pKd - 3
pKd 9.8 (Kd 1.5x10-10 M) [3]
BLT1 receptor Mm Agonist Full agonist 9.2 pKd - 1
pKd 9.2 (Kd 6x10-10 M) [1]
BLT1 receptor Rn Agonist Full agonist 9.2 pKd - 2
pKd 9.2 (Kd 6.7x10-10 M) [2]
BLT2 receptor Hs None - 7.6 – 9.7 pKd -
pKd 7.6 – 9.7 (Kd 2.3x10-8 – 2x10-10 M)