Ligand id: 3413

Name: [3H]LTB4    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 14
Topological polar surface area 77.76
Molecular weight 336.23
XLogP 4.5
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Huang WW, Garcia-Zepeda EA, Sauty A, Oettgen HC, Rothenberg ME, Luster AD. (1998)
Molecular and biological characterization of the murine leukotriene B4 receptor expressed on eosinophils.
J. Exp. Med., 188 (6): 1063-74. [PMID:9743525]
2. Toda A, Yokomizo T, Masuda K, Nakao A, Izumi T, Shimizu T. (1999)
Cloning and characterization of rat leukotriene B4 receptor.
Biochem. Biophys. Res. Commun., 262: 806-812. [PMID:10471406]
3. Yokomizo T, Izumi T, Chang K, Takuwa Y, Shimizu T. (1997)
A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis.
Nature, 387: 620-624. [PMID:9177352]