myo-inositol   Click here for help

GtoPdb Ligand ID: 4495

Synonyms: D-myo-inositol
PDB Ligand
Compound class: Metabolite
Comment: PubChem CID 892 shows the non-chiral inositol structure
2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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Physico-chemical Properties
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Physico-chemical Properties

Calculated molecular properties are available for small molecules and natural products (not peptides). Properties were generated using the CDK toolkit. All properties were selected to enable the prediction of the Lipinski Rule-of-Five profile or ‘druglikeness’ for each ligand. For more info on each category see the help pages.

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Hydrogen bond acceptors 6
Hydrogen bond donors 6
Rotatable bonds 0
Topological polar surface area 121.38
Molecular weight 180.06
XLogP -1.46
No. Lipinski's rules broken 1
SMILES / InChI / InChIKey
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SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

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Canonical SMILES OC1C(O)C(O)C(C(C1O)O)O
Isomeric SMILES O[C@@H]1[C@H](O)[C@H](O)[C@H]([C@@H]([C@H]1O)O)O
InChI InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H/t1-,2-,3-,4+,5-,6-
InChI Key CDAISMWEOUEBRE-GPIVLXJGSA-N
Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
Proton myo-inositol cotransporter 3
SMIT 2
SGLT6 1
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Substrates at SGLT6 myo-inositol = D-chiro-inositol> D-glucose > D-xylose > L-xylose 1
Substrates at SMIT myo-inositol, scyllo-inositol > L-fucose > L-xylose > L-glucose, D-glucose, α-MDG > D-galactose, D-fucose > D-xylose 2
Ligand mentioned in the following text fields
Inositol monophosphatase overview
SLC2 family of hexose and sugar alcohol transporters overview
SLC5 family of sodium-dependent glucose transporters overview
Sodium myo-inositol cotransporter transporters overview