IFN-γ   

GtoPdb Ligand ID: 4968

Synonyms: Actimmune® | immune interferon | interferon gamma
IFN-γ is an approved drug (FDA (1999))
Comment: IFN-γ is a type II interferon. It is biologically active as a homodimer.
Species: Human
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Natural/Endogenous Targets
Target
Interferon-γ receptor
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Interferon-γ receptor Hs Agonist Agonist - - -
Other ligands which bind to or alter the activity of this ligand
Key to terms and symbols Click column headers to sort
Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
emapalumab Hs Antibody Binding 9.1 pKd - 1
pKd 9.1 (Kd 7.32x10-10 M) [1]
Description: Measured using Biacore technology
fontolizumab Hs Antibody Binding - - - 2
[2]