IL-10   Click here for help

GtoPdb Ligand ID: 4975

Synonyms: interleukin-10
Immunopharmacology Ligand
Comment: Biologically active IL-10 is a homodimer. It is an anti-inflammatory cytokine.
Species: Human
Click here for help
Natural/Endogenous Targets
Interleukin-10 receptor
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Interleukin 10 receptor, α subunit Hs Agonist Agonist 9.7 – 10.3 pEC50 - 2
pEC50 9.7 – 10.3 (EC50 2x10-10 – 5x10-11 M) [2]
Interleukin-10 receptor Ligand is endogenous in the given species Hs Agonist Agonist - - -