resiquimod

Ligand id: 5051

Name: resiquimod

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 86.19
Molecular weight 314.17
XLogP 1.94
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
TLR7 Hs Agonist Agonist 5.9 pEC50 - 1-3
pEC50 5.9 (EC50 1.34x10-6 M) [1-3]
TLR8 Hs Agonist Agonist 5.2 pEC50 - 1-3
pEC50 5.2 (EC50 6.13x10-6 M) [1-3]