Synonyms: lipoxin B4
Compound class:
Metabolite
Comment: Lipoxin B4 (LXB4) is a member of the lipoxin family. In inflammation it acts as a proresolving mediator [8].
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Targets where the ligand is described in the comment field | |
Target | Comment |
CYP4F3 | Responsible for ω-hydroxylation of LTB4, LXB4 [7] and polyunsaturated fatty acids [2-3], and ω-hydroxylation of fatty acid epoxides [6]. Possible role in Crohn's disease [1]. |
CYP4F2 | Responsible for ω-hydroxylation of LTB4, LXB4 [7], and tocopherols, including vitamin E [9]. Associated with the warfarin response [10]. |
Ligand mentioned in the following text fields |
Leukotriene and lipoxin metabolism overview |
Leukotriene receptors comments |