CSC

Ligand id: 5609

Name: CSC

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 61.82
Molecular weight 330.09
XLogP 4.4
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
A2A receptor Rn Antagonist Antagonist 7.3 pKi - 2
pKi 7.3 (Ki 5.4x10-8 M) [2]
A2B receptor Rn Antagonist Antagonist 5.1 pKi - 1
pKi 5.1 (Ki 8.2x10-6 M) [1]
A3 receptor Rn Antagonist Antagonist <5.0 pKi - 3
pKi <5.0 (Ki >1x10-5 M) [3]
A1 receptor Rn Antagonist Antagonist 4.6 pKi - 2
pKi 4.6 (Ki 2.8x10-5 M) [2]