compound 2g [PMID: 19309152]

Ligand id: 5791

Name: compound 2g [PMID: 19309152]

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 103.93
Molecular weight 377.14
XLogP 2.79
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
HCA2 receptor Hs Agonist Full agonist 7.9 pIC50 - 1
pIC50 7.9 (IC50 1.3x10-8 M) [1]