7-methoxy-1-naphthylpiperazine   Click here for help

GtoPdb Ligand ID: 6

Compound class: Synthetic organic
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 50.86
Molecular weight 275.14
XLogP 2.41
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES O=C(OCC1OC1)NCC[Si]([Si](C)(C)C)(C)C
Isomeric SMILES O=C(OCC1OC1)NCC[Si]([Si](C)(C)C)(C)C
InChI InChI=1S/C11H25NO3Si2/c1-16(2,3)17(4,5)7-6-12-11(13)15-9-10-8-14-10/h10H,6-9H2,1-5H3,(H,12,13)
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
5-HT1D receptor Hs Agonist Full agonist 9.2 pKi - 1
pKi 9.2 [1]
5-HT1B receptor Hs Agonist Full agonist 8.7 pKi - 1
pKi 8.7 [1]
5-HT1A receptor Hs Agonist Full agonist 8.6 pKi - 1
pKi 8.6 [1]