IL-27   Click here for help

GtoPdb Ligand ID: 6151

Immunopharmacology Ligand
Comment: IL-27 is an IL-12 family cytokine. It is a heterodimeric cytokine that contains an α and a β subunit and is expressed by activated antigen presenting cells [1]. IL-27 interaction with its receptor complex activates the JAK/STAT and p38 MAPK pathways.
Species: Human
Natural/Endogenous Targets
Target
Interleukin-27 receptor
Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Interleukin-27 receptor Ligand is endogenous in the given species Hs Agonist Agonist - - -