ML SA1

Ligand id: 6386

Name: ML SA1

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 57.69
Molecular weight 362.16
XLogP 3.6
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
TRPML2 Hs Activator Activation - - 1x10-5 1
Conc range: 1x10-5 M [1]
Voltage: -140.0 mV
TRPML3 Hs Activator Activation - - 1x10-5 1
Conc range: 1x10-5 M [1]
Voltage: -140.0 mV
TRPML1 Hs Activator Activation 7.3 pEC50 - 1
pEC50 7.3 [1]
Voltage: -140.0 mV