fibronectin   Click here for help

GtoPdb Ligand ID: 6754

Comment: The structure of mature human fibronectin varies according to the splice variants of the proteins cleaved from the precursor. Heteromeric, monomeric and homomeric variants exist. For more details, see the UniProt entry for this protein.
Species: Human
Bioactivity Comments
Rare genetic variants in FN1 appear to counteract the detrimental effects of the APOEε4 allele that is associated with Alzheimer's disease risk [1], likely by permitting better clearance of toxic amyloid out of the brain.
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields