Synonyms: Co-phenotrope | diphenoxylate HCl | Lomotil®
diphenoxylate is an approved drug
Compound class:
Synthetic organic
Comment: Diphenoxylate is a phenylpiperidine series, centrally-active opioid antidiarrheal drug. Diphenoxylate is metabolised in vivo to form difenoxin. Both diphenoxylate and difenoxin can be prescribed in fixed-dose combination with atropine to act as an abuse deterrent. Atropine causes severe weakness and nausea if standard doses are exceeded.
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Bioactivity Comments |
We have been unable to find publicly available affinity data for this drug at its proposed molecular target to substantiate its MMOA, and have therefore not tagged a primary drug target. |