Synonyms: Co-phenotrope | diphenoxylate HCl | Lomotil®
diphenoxylate is an approved drug
Compound class:
Synthetic organic
Comment: Diphenoxylate is a phenylpiperidine series, centrally-active opioid antidiarrheal drug. Diphenoxylate is metabolised in vivo to form difenoxin. Both diphenoxylate and difenoxin can be prescribed in fixed-dose combination with atropine to act as an abuse deterrent. Atropine causes severe weakness and nausea if standard doses are exceeded.
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