fosphenytoin   Click here for help

GtoPdb Ligand ID: 7190

Synonyms: ACC-9653-010 | Cerebyx® | CI-982 | Sesquient®
Approved drug
fosphenytoin is an approved drug (FDA (1996))
Compound class: Synthetic organic
Comment: Fosphenytoin is a prodrug of phenytoin. This drug is an anticonvulsant.
Marketed formulations may contain fosphenytoin sodium (PubChem CID 56338).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 129.47
Molecular weight 362.07
XLogP 1.15
No. Lipinski's rules broken 0
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Canonical SMILES O=C1N(COP(=O)(O)O)C(=NC1(c1ccccc1)c1ccccc1)O
Isomeric SMILES O=C1N(COP(=O)(O)O)C(=NC1(c1ccccc1)c1ccccc1)O
InChI InChI=1S/C16H15N2O6P/c19-14-16(12-7-3-1-4-8-12,13-9-5-2-6-10-13)17-15(20)18(14)11-24-25(21,22)23/h1-10H,11H2,(H,17,20)(H2,21,22,23)
Bioactivity Comments
If this compound is a prodrug it may have little or no measurable bioactivity at the molecular target of its active counterpart. Therefore, we have not tagged a primary drug target.