L-glutamine   Click here for help

GtoPdb Ligand ID: 723

PDB Ligand
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 106.41
Molecular weight 146.07
XLogP -4.08
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES NC(=O)CCC(C(=O)O)N
Isomeric SMILES NC(=O)CC[C@@H](C(=O)O)N
InChI InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
InChI Key ZDXPYRJPNDTMRX-VKHMYHEASA-N
Natural/Endogenous Targets
Target
GPRC6 receptor
Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
Alanine/serine/cysteine transporter 2
sodium-coupled neutral amino acid transporter 2 4
Sodium-coupled neutral amino acid transporter 5 6
NTT4 9
sodium-coupled neutral amino acid transporter 1 1
Sodium-coupled neutral amino acid transporter 3 2
sodium-coupled neutral amino acid transporter 4 3
B0AT3 7
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
GPRC6 receptor Ligand is endogenous in the given species Hs Agonist Full agonist 3.2 pEC50 - 8
pEC50 3.2 [8]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Targets where the ligand is described in the comment field
Target Comment
Ligand mentioned in the following text fields