CCL8   Click here for help

GtoPdb Ligand ID: 772

Synonyms: monocyte chemotactic protein-2
Immunopharmacology Ligand
Comment: CCL8 (also known as MCP-2) is a CC family chemokine.
Species: Human
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Natural/Endogenous Targets
Target
CCR1
CCR2
CCR3
CCR5
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CCR5 Ligand is endogenous in the given species Hs Agonist Full agonist 9.3 pKi - 4
pKi 9.3 [4]
CCR2 Ligand is endogenous in the given species Hs Agonist Full agonist 8.6 pIC50 - 2
pIC50 8.6 [2]
CCR1 Ligand is endogenous in the given species Hs Agonist Agonist - - -
CCR3 Ligand is endogenous in the given species Hs Agonist Full agonist - - -
CCR8 Ligand is endogenous in the given species Hs Agonist Agonist - - -
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference