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Molecular properties generated using the CDK
|ASP-3026 is effective against NPM-ALK⁺ T-cell anaplastic large-cell lymphoma in vitro and in vivo . It also effective against tumour cells expressing the EML4-ALK rearrangement, even when possessing a crizotinib-resistance-conferring gatekeeper mutation (L1196M)  (in vivo and in vitro results).
We have been unable to find affinity data for ASP-3026 using recombinant ALK protein.