Ligand id: 7740

Name: ASP-3026

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 124.2
Molecular weight 580.29
XLogP 4.1
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
ASP-3026 is currently being assessed in clinical trials. Click here to view the list of ASP-3026 trials currently registered with
Mechanism Of Action and Pharmacodynamic Effects
ASP3026 inhibits ALK activity in an ATP-competitive manner, ie it acts at the enzyme's ATP binding [2].