Ligand id: 7749

Name: dusigitumab

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
Despite peptide matches suggesting that dusigitumab is antibody 7_159_1 (or 7.159.1) in patent US7939637 [2], no data is presented for this clone. Data is presented for 7.159.2, but crucially no sequence data is available. The binding data we present here is for antibody clone 7.159.2 as a representative example from the patent.
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
insulin-like growth factor 2 Hs Antibody Binding 11.5 pKd - 2
pKd 11.5 (Kd 2.9x10-12 M) [2]
insulin-like growth factor 1 Hs Antibody Binding 9.7 pKd - 2
pKd 9.7 (Kd 2.16x10-10 M) [2]